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中文:牛磺酸去氧膽酸
中文同義詞: ?；敲撗跄懰?牛鈉;?；撬嵝苊撗跄懰??；切苊撗跄懰徕c鹽;?；撬嵝苋ッ撗跄懰??；切苊撗跄懰??；切廴パ跄懰?牛磺
英文名稱(chēng): TAUROURSODEOXYCHOLIC ACID
英文同義詞: 3ALPHA,7BETA-DIHYDROXY-5BETA-CHOLAN-24-OIC ACID N-(2-SULFOETHYL)AMIDE;TAUROURSODEOXYCHOLIC ACID;TAUROURSODESOXYCHOLIC ACID;2-(((3-alpha,5-beta,7-beta)-3,7-dihydroxy-24-oxocholan-24-ethanesulfonicaci;2-(((3-alpha,5-beta,7-beta)-3,7-dihydroxy-24-oxocholan-24-yl)amino)ethanesul;fonicacid;n-(3-alpha,7-beta-dihydroxy-5-beta-cholan-24-oyl)-taurin;ur906
CAS號(hào): 14605-22-2
分子式: C26H45NO6S
分子量: 499.7
EINECS號(hào):
相關(guān)類(lèi)別: 中草藥成分;Miscellaneous Natural Products;Bile Acids;Biochemistry;Steroids;Chiral Reagents;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;中藥對(duì)照品;Herb extract;對(duì)照品、標(biāo)準(zhǔn)品;生化試劑;其它試劑;原料藥;植物提取物;對(duì)照品;膽酸系列;醫(yī)藥原料藥;標(biāo)準(zhǔn)品
Mol文件: 14605-22-2.mol
牛鈉 性質(zhì)
熔點(diǎn) 173-175°C
折射率 46 ° (C=1, EtOH)
CAS 數(shù)據(jù)庫(kù) 14605-22-2(CAS DataBase Reference)
牛鈉 用途與合成方法
藥物作用及臨床應(yīng)用 牛鈉又稱(chēng)牛磺、?；切苊撗跄懰幔瘜W(xué)名稱(chēng)為3α，7β二羥基膽烷酰-N-?；撬幔饕谴嬖谟诤谛苣懼?，是熊膽中標(biāo)志性有效成分。具有解痙、抗驚厥、抗炎及溶膽石等作用。
現(xiàn)代合成藥物?；?，是由的梭基與牛磺酸的氨基之間縮水而成的結(jié)合型膽汁酸。國(guó)外?；悄z囊已經(jīng)上市，2007年作為進(jìn)口藥品獲準(zhǔn)在中國(guó)銷(xiāo)售，臨床主要用于治療膽囊膽固醇結(jié)石、原發(fā)硬化性膽管炎、原發(fā)膽汁性肝硬化和慢性丙型病毒性肝炎等。目前牛磺原料藥及其制劑在中國(guó)還沒(méi)有藥品注冊(cè)。
牛鈉是從熊膽汁中分離出來(lái)一種天然膽汁酸，屬化學(xué)制劑，在體內(nèi)與牛磺酸結(jié)合存在于膽汁中，是一種親水性膽酸，為一種膽固醇結(jié)石溶解劑。能減少對(duì)膽固醇的分泌，降低膽汁中膽固醇的飽和度，促進(jìn)膽汁酸的分泌，增加膽固醇在膽汁中的溶解度，使膽固醇結(jié)石溶解或防止結(jié)石的形成?？稍黾幽懼置诹?，松弛膽管口括約肌產(chǎn)生利膽作用，有利于結(jié)石的排出。本品不能溶解其他類(lèi)型的膽結(jié)石。適用于治療膽固醇性結(jié)石、高脂血癥、膽汁分泌障礙性疾病、原發(fā)性膽汁性肝硬化、慢性肝炎、膽汁反流性胃炎和預(yù)防肝移植急性排斥及反應(yīng)。本品的溶石作用略弱于鵝去氧膽酸。
以上信息由Chemicalbook的Andy編輯整理。
含量：98%以上
是否合成：是（有天然提?。?/strong>
包裝：1kg鋁箔袋 5kg紙板桶
銷(xiāo)售指導(dǎo)價(jià)：8600/kg
Chinese: ursodeoxycholic acid taurine
Chinese Synonyms: taurodeoxycholic acid; CBBC sodium deoxycholate; ursodeoxycholic acid taurine; tauro ursodeoxycholic acid sodium salt; taurine bear to deoxycholate; tauro ursodeoxycholic acid; taurocholic male deoxycholate; tauroursodeoxycholic acid
English name: TAUROURSODEOXYCHOLIC ACID
English Synonyms: 3ALPHA, 7BETA-DIHYDROXY-5BETA-CHOLAN-24-OIC ACID N- (2-SULFOETHYL) AMIDE; TAUROURSODEOXYCHOLIC ACID; TAUROURSODESOXYCHOLIC ACID; 2 - (((3-alpha, 5-beta, 7-beta) - 3,7-dihydroxy-24-oxocholan-24-ethanesulfonicaci; 2 - (((3-alpha, 5-beta, 7-beta) -3,7-dihydroxy-24-oxocholan-24-yl) amino) ethanesul; fonicacid; n- (3-alpha, 7-beta-dihydroxy-5-beta-cholan-24-oyl) -taurin; ur906
CAS: 14605-22-2
Formula: C26H45NO6S
Molecular weight: 499.7
EINECS:
Related Categories: herbal ingredients; Miscellaneous Natural Products; Bile Acids; Biochemistry; Steroids; Chiral Reagents; Inhibitors; Intermediates & Fine Chemicals; Pharmaceuticals; medicine reference substance; Herb extract; Controls, Standards; biochemical reagents; other reagents; APIs ; plant extracts; reference; acid series; pharmaceutical raw materials; standard
Mol File: 14605-22-2.mol
CBBC sodium deoxycholate nature
Melting point of 173-175 ° C
Refractive index of 46 ° (C = 1, EtOH)
CAS databases 14605-22-2 (CAS DataBase Reference)
CBBC sodium deoxycholate Usage And Synthesis
CBBC drug action and clinical application, also known as sodium deoxycholate tauroursodeoxycholic acid, taurocholic ursodeoxycholic acid, the chemical name for 3α, 7β-dihydroxy-bile alkanoylthio -N- taurine, mainly exist in black bear bile, is the active ingredient in bear bile iconic. Has antispasmodic, anti-convulsants, anti-inflammatory and dissolve gallstones and so on.
Modern synthetic drugs tauroursodeoxycholic acid, is a shuttle between ursodeoxycholic acid and taurine amino group formed by shrinking conjugated bile acids. Foreign tauroursodeoxycholic acid capsule has been listed in 2007 as
CBBC sodium deoxycholate is separated from the bear bile out of a natural bile acid, is a chemical in the body combined with taurine is present in the bile, is a hydrophilic bile acid, as a cholesterol gallstones solubilizer. Can reduce the secretion of cholesterol in the liver, reducing the saturation of bile cholesterol, promote the secretion of bile acids, increases the solubility of cholesterol in the bile, cholesterol stones dissolve or prevent stone formation. Increase the secretion of bile, bile duct mouth sphincter relaxation produced choleretic effect, conducive to the discharge of stones. This product can not dissolve other types of gallstones. For the treatment of cholesterol stones, hyperlipidemia, bile secretion disorders, primary biliary cirrhosis, chronic hepatitis, bile reflux gastritis and prevention of acute rejection in liver transplantation and reactions. RONGSHI effect of this product is slightly weaker than chenodeoxycholic acid.
The above information is edited by Chemicalbook of Andy.
Content: 98% or more
Whether synthesis: is (a natural extract)
Packaging: 1kg aluminum foil bag 5kg cardboard
Sales guide price: 8600 / kg
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